Based on the 90's cartoon, Biker Mice From Mars, this story follows a race of mice living on Mars fighting a war against the Plutarkians, a violent amphibious-like species from outside the galaxy. Although their master plan is unclear, the mice won't give up their home without a fight. Three soldiers, Vinnie, Modo, and Throttle, find themselves at the frontlines of a war to save their kind. Throttle has been promoted to a new position in the mice army where he is forced to sit behind a desk and use his mind instead of his fists while his old unit is sent out into battle. Will Throttle obey orders and let his team go out on a mission without him? Or will Throttle do what he does best and lead his troops head-on into fight with the evil Plutarkians?