FLUORINE IN PHARMACEUTICAL AND MEDICINAL CHEMISTRY: FROM

FLUORINE IN PHARMACEUTICAL AND MEDICINAL CHEMISTRY: FROM BIOPHYSICAL ASPECTS TO CLINICAL APPLICATIONS (Molecular Medicine and Medicinal Chemistry, 6)

Fluorine chemistry is an expanding area of research that is attracting international interest, due to the impact of fluorine in drug discovery and in clinical and molecular imaging (e.g. PET, MRI). Many researchers and academics are entering this area of research, while scientists in industrial and clinical environments are also indirectly exposed to fluorine chemistry through the use of fluorinated compounds for imaging.This book provides an overview of the impact that fluorine has made in the life sciences. In the first section, the emphasis is on how fluorine substitution of amino acids, peptides, nucleobases and carbohydrates can provide invaluable information at a molecular level. The following chapters provide answers to the key questions posed on the importance of fluorine in drug discovery and clinical applications. For examples, the reader will discover how fluorine has found its place as a key element improving drug efficacy, with reference to some of the best-selling drugs on the market. Finally, a thorough review on the design, synthesis and use of 18F-radiotracers for positron emission tomography is provided, and this is complemented with a discussion on how 19F NMR has advanced molecular and clinical imaging.
Country USA
Brand Imperial College Press
Manufacturer Imperial College Pr
Binding Hardcover
ItemPartNumber Illustrations (some col.)
UnitCount 1
EANs 9781848166349
ReleaseDate 0000-00-00

Country	USA
Brand	Imperial College Press
Manufacturer	Imperial College Pr
Binding	Hardcover
ItemPartNumber	Illustrations (some col.)
UnitCount	1
EANs	9781848166349
ReleaseDate	0000-00-00

FLUORINE IN PHARMACEUTICAL AND MEDICINAL CHEMISTRY: FROM BIOPHYSICAL ASPECTS TO CLINICAL APPLICATIONS (Molecular Medicine and Medicinal Chemistry, 6)

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