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Oral Bioavailability Assessment: Basics and Strategies for Drug Discovery and Development (Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods)

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Oral Bioavailability Assessment: Basics and Strategies for Drug Discovery and Development (Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods)

Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability â€“ one of the most significant hurdles in drug discovery and development.

â€¢Â Â Â Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability
â€¢Â Â Â Helps readers reduce the failure rate of drug candidates when transitioning from the bench to the clinic during development
â€¢Â Â Â Explains how preclinical animal models â€“ used in preclinical testing â€“ and in vitro tools translate to humans, which is an underappreciated and complicated area of drug development
â€¢Â Â Â Includes chapters about pharmacokineticÂ modelling, the Biopharmaceutics Drug Disposition Classification System (BDDCS), and the Extended Clearance Classification System (ECCS)
â€¢Â Â Â Has tutorials for applying strategies to medicinal chemistry practices of drug discovery/development
Country USA
Brand Wiley
Manufacturer Wiley
Binding Hardcover
UnitCount 1
EANs 9781118916698
ReleaseDate 0000-00-00

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